Kinin B1 receptor: a potential therapeutic target in sepsis-induced vascular hyperpermeability

BACKGROUND: In sepsis, the endothelial barrier becomes incompetent, with the leaking of plasma into interstitial tissues. VE-cadherin, an adherens junction protein, is the gatekeeper of endothelial cohesion. Kinins, released during sepsis, induce vascular leakage and vasodilation. They act via two G...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Ruiz, Stéphanie, Vardon-Bounes, Fanny, Buléon, Marie, Guilbeau-Frugier, Céline, Séguelas, Marie-Hélène, Conil, Jean-Marie, Girolami, Jean-Pierre, Tack, Ivan, Minville, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7168845/
https://ncbi.nlm.nih.gov/pubmed/32306971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-020-02342-8
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados