Sepsis modeling in mice: ligation length is a major severity factor in cecal ligation and puncture

BACKGROUND: The cecal ligation and puncture (CLP) model, a gold standard in sepsis research, is associated with an important variability in mortality. While the number of punctures and needle size is well described in CLP animal studies, the length of cecal ligation is often not. The relationship be...

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Vydáno v:Intensive Care Med Exp
Hlavní autoři: Ruiz, Stéphanie, Vardon-Bounes, Fanny, Merlet-Dupuy, Virginie, Conil, Jean-Marie, Buléon, Marie, Fourcade, Olivier, Tack, Ivan, Minville, Vincent
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2016
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4949182/
https://ncbi.nlm.nih.gov/pubmed/27430881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40635-016-0096-z
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