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Sepsis modeling in mice: ligation length is a major severity factor in cecal ligation and puncture

BACKGROUND: The cecal ligation and puncture (CLP) model, a gold standard in sepsis research, is associated with an important variability in mortality. While the number of punctures and needle size is well described in CLP animal studies, the length of cecal ligation is often not. The relationship be...

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Detalhes bibliográficos
Publicado no:Intensive Care Med Exp
Main Authors: Ruiz, Stéphanie, Vardon-Bounes, Fanny, Merlet-Dupuy, Virginie, Conil, Jean-Marie, Buléon, Marie, Fourcade, Olivier, Tack, Ivan, Minville, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4949182/
https://ncbi.nlm.nih.gov/pubmed/27430881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40635-016-0096-z
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