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Kininase 1 As a Preclinical Therapeutic Target for Kinin B(1) Receptor in Insulin Resistance

Kinin B1 receptor (B1R) contributes to insulin resistance, an early event in type 2 diabetes, through the upregulation and activation of the inducible form of nitric oxide synthase (iNOS), pro-inflammatory cytokines and the oxidative stress. This study addresses the hypothesis that inhibition of kin...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Haddad, Youssef, Couture, Réjean
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5539221/
https://ncbi.nlm.nih.gov/pubmed/28824433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00509
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