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The methyltransferase PRMT6 attenuates antiviral innate immunity by blocking TBK1–IRF3 signaling

Protein arginine methyltransferases (PRMTs) play diverse biological roles and are specifically involved in immune cell development and inflammation. However, their role in antiviral innate immunity has not been elucidated. Viral infection triggers the TBK1–IRF3 signaling pathway to stimulate the pro...

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Detalhes bibliográficos
Publicado no:Cell Mol Immunol
Main Authors: Zhang, Hua, Han, Chaofeng, Li, Tianliang, Li, Nan, Cao, Xuetao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6804946/
https://ncbi.nlm.nih.gov/pubmed/29973649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-018-0057-4
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