Inhibition of Antiviral Innate Immunity by Avibirnavirus VP3 via Blocking TBK1-TRAF3 Complex Formation and IRF3 Activation

The host innate immune system develops various strategies to antagonize virus infection, and the pathogen subverts or evades host innate immunity for self-replication. In the present study, we discovered that Avibirnavirus infectious bursal disease virus (IBDV) VP3 protein significantly inhibits MDA...

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Vydáno v:mSystems
Hlavní autoři: Deng, Tingjuan, Hu, Boli, Wang, Xingbo, Lin, Lulu, Zhou, Jianwei, Xu, Yuting, Yan, Yan, Zheng, Xiaojuan, Zhou, Jiyong
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2021
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8125067/
https://ncbi.nlm.nih.gov/pubmed/33975961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSystems.00016-21
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