Immunotherapy of Relapsed and Refractory Solid Tumors With Ex Vivo Expanded Multi-Tumor Associated Antigen Specific Cytotoxic T Lymphocytes: A Phase I Study

PURPOSE: Tumor-associated antigen cytotoxic T cells (TAA-Ts) represent a new, potentially effective and nontoxic therapeutic approach for patients with relapsed or refractory solid tumors. In this first-in-human trial, we investigated the safety of administering TAA-Ts that target Wilms tumor gene 1...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: Hont, Amy B., Cruz, C. Russell, Ulrey, Robert, O’Brien, Barbara, Stanojevic, Maja, Datar, Anushree, Albihani, Shuroug, Saunders, Devin, Hanajiri, Ryo, Panchapakesan, Karuna, Darko, Sam, Banerjee, Payal, Fortiz, Maria Fernanda, Hoq, Fahmida, Lang, Haili, Wang, Yunfei, Hanley, Patrick J., Dome, Jeffrey S., Bollard, Catherine M., Meany, Holly J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2019
Assuntos:
Original Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6804838/
https://ncbi.nlm.nih.gov/pubmed/31356143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.19.00177
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