EPCT-24 THE REMIND TRIAL: MULTI-ANTIGEN TARGETED T CELLS FOR PEDIATRIC CNS TUMORS

BACKGROUND: Patients with relapsed CNS malignancies or DIPG face terrible prognoses. We hypothesized that T cells specific for 3 tumor-associated antigens (TAA), WT1, PRAME and survivin, would be safe and elicit anti-tumor immunity. METHODS: Patients (n=18) received autologous tumor antigen-associat...

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Bibliografiska uppgifter
I publikationen:Neuro Oncol
Huvudupphovsmän: Grant, Melanie, Fortiz, Maria, Wang, Lu, Lang, Haili, Datar, Anushree, Reynolds, Emily, Terpilowski, Madeleine, Geiger, Ashley, Lazarski, Chris, Tanna, Jay, Pitino, Adriana, Zhang, Nan, Hoq, Fahmida, Hanley, Patrick, Cruz, C Russell, Kilburn, Lindsay, Packer, Roger, Rood, Brian, Bollard, Catherine
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2021
Ämnen:
Translational/Early Phase Clinical Trials
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168094/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noab090.210
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