Identification of Novel HLA-Restricted PRAME Peptides to Facilitate off-the-shelf Tumor- Associated Antigen-specific T-cell Therapies

BACKGROUND: Preferentially expressed antigen in melanoma (PRAME) is a cancer-testis antigen overexpressed in many human malignancies while poorly expressed or absent in healthy tissues, making it a good target for anticancer immunotherapy. Development of an effective off-the-shelf adoptive T-cell th...

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Publicado no:Cytotherapy
Main Authors: Stanojevic, Maja, Hont, Amy B., Geiger, Ashley, O’Brien, Samuel, Ulrey, Robert, Grant, Melanie, Datar, Anushree, Lee, Ping-Hsien, Lang, Haili, Cruz, Conrad R.Y., Hanley, Patrick J., Barrett, A. John, Keller, Michael D., Bollard, Catherine M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316284/
https://ncbi.nlm.nih.gov/pubmed/33832817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcyt.2021.03.001
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