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Removal of Endotoxin from rAAV Samples Using a Simple Detergent-Based Protocol

Endotoxin is the most common contaminant found in protein samples. Even a small amount of endotoxin can induce strong allergic reaction and death of a host organism. Endotoxin is also often detected in recombinant adeno-associated virus (rAAV) stocks prepared in research laboratories using off-the-s...

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Vydáno v:Mol Ther Methods Clin Dev
Hlavní autoři: Kondratova, Liudmyla, Kondratov, Oleksandr, Ragheb, Ragy, Zolotukhin, Sergei
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Gene & Cell Therapy 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6804492/
https://ncbi.nlm.nih.gov/pubmed/31649960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2019.08.013
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