Myostatin Inhibition Using ActRIIB-mFc Does Not Produce Weight Gain or Strength in the Nebulin Conditional KO Mouse

Mutations in at least 12 genes are responsible for a group of congenital skeletal muscle diseases known as nemaline myopathies (NMs). NMs are associated with a range of clinical symptoms and pathological changes often including the presence of cytoplasmic rod-like structures (nemaline bodies) and my...

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Vydáno v:J Neuropathol Exp Neurol
Hlavní autoři: Tinklenberg, Jennifer A, Siebers, Emily M, Beatka, Margaret J, Fickau, Brittany A, Ayres, Samuel, Meng, Hui, Yang, Lin, Simpson, Pippa, Granzier, Henk L, Lawlor, Michael W
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6804412/
https://ncbi.nlm.nih.gov/pubmed/30597051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nly120
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