Myostatin blockage using actRIIB antagonism in mice bearing the Lewis lung carcinoma results in the improvement of muscle wasting and physical performance

BACKGROUND: Cachexia is a multiorganic syndrome associated with cancer, characterized by body weight loss, muscle and adipose tissue wasting and inflammation. METHODS: The aim of this investigation was to examine the effect of the soluble receptor antagonist of myostatin (sActRIIB) in cachectic tumo...

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Autors principals: Busquets, Sílvia, Toledo, Míriam, Orpí, Marcel, Massa, David, Porta, Maria, Capdevila, Eva, Padilla, Núria, Frailis, Valentina, López-Soriano, Francisco J., Han, H. Q., Argilés, Josep M.
Format: Artigo
Idioma:Inglês
Publicat: Springer-Verlag 2011
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302990/
https://ncbi.nlm.nih.gov/pubmed/22450815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13539-011-0049-z
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