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Blockade of ActRIIB Signaling Triggers Muscle Fatigability and Metabolic Myopathy
Myostatin regulates skeletal muscle size via the activin receptor IIB (ActRIIB). However, its effect on muscle energy metabolism and energy-dependent muscle function remains largely unexplored. This question needs to be solved urgently since various therapies for neuromuscular diseases based on bloc...
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Publicado no: | Mol Ther |
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Main Authors: | , , , , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4435590/ https://ncbi.nlm.nih.gov/pubmed/24861054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.90 |
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