Chargement en cours...
Small-Molecule Inhibition of UBE2T/FANCL-Mediated Ubiquitylation in the Fanconi Anemia Pathway
[Image: see text] The Fanconi anemia pathway orchestrates the repair of DNA interstrand cross-links and stalled replication forks. A key step in this pathway is UBE2T and FANCL-dependent monoubiquitylation of the FANCD2-FANCI complex. The Fanconi anemia pathway represents an attractive therapeutic t...
Enregistré dans:
| Publié dans: | ACS Chem Biol |
|---|---|
| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Chemical
Society
2019
|
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6804243/ https://ncbi.nlm.nih.gov/pubmed/31525021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00570 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|