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Dendritic Cells Require PINK1-Mediated Phosphorylation of BCKDE1α to Promote Fatty Acid Oxidation for Immune Function
Dendritic cell (DCs) activation by Toll-like receptor (TLR) agonist induces robust metabolic rewiring toward glycolysis. Recent findings in the field identified mechanistic details governing these metabolic adaptations. However, it is unknown whether a switch to glycolysis from oxidative phosphoryla...
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| Published in: | Front Immunol |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Frontiers Media S.A.
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6803436/ https://ncbi.nlm.nih.gov/pubmed/31681280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02386 |
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