Genetic heterogeneity within collective invasion packs drives leader and follower cell phenotypes

Collective invasion, the coordinated movement of cohesive packs of cells, has become recognized as a major mode of metastasis for solid tumors. These packs are phenotypically heterogeneous and include specialized cells that lead the invasive pack and others that follow behind. To better understand h...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Cell Sci
Main Authors: Zoeller, Elizabeth L., Pedro, Brian, Konen, Jessica, Dwivedi, Bhakti, Rupji, Manali, Sundararaman, Niveda, Wang, Lei, Horton, John R., Zhong, Chaojie, Barwick, Benjamin G., Cheng, Xiaodong, Martinez, Elisabeth D., Torres, Matthew P., Kowalski, Jeanne, Marcus, Adam I., Vertino, Paula M.
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists Ltd 2019
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803364/
https://ncbi.nlm.nih.gov/pubmed/31515279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.231514
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