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Tissue-specific roles of p73 in development and homeostasis

p73 (TP73) belongs to the p53 family of transcription factors. Its gene locus encodes two opposing types of isoforms, the transcriptionally active TAp73 class and the dominant-negative DNp73 class, which both play critical roles in development and homeostasis in an astonishingly diverse array of bio...

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Bibliographic Details
Published in:J Cell Sci
Main Authors: Nemajerova, Alice, Moll, Ute M.
Format: Artigo
Language:Inglês
Published: The Company of Biologists Ltd 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803362/
https://ncbi.nlm.nih.gov/pubmed/31582429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.233338
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