Interleukin-22 (IL-22) Binding Protein Constrains IL-22 Activity, Host Defense, and Oxidative Phosphorylation Genes during Pneumococcal Pneumonia

Streptococcus pneumoniae is the most common cause of community-acquired pneumonia worldwide, and interleukin-22 (IL-22) helps contain pneumococcal burden in lungs and extrapulmonary tissues. Administration of IL-22 increases hepatic complement 3 and complement deposition on bacteria and improves pha...

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Опубликовано в: :Infect Immun
Главные авторы: Trevejo-Nunez, Giraldina, Elsegeiny, Waleed, Aggor, Felix E. Y., Tweedle, Jamie L., Kaplan, Zoe, Gandhi, Pranali, Castillo, Patricia, Ferguson, Annabel, Alcorn, John F., Chen, Kong, Kolls, Jay K., Gaffen, Sarah L.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2019
Предметы:
Host Response and Inflammation
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803344/
https://ncbi.nlm.nih.gov/pubmed/31451621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00550-19
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