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Novel Functions of IFI44L as a Feedback Regulator of Host Antiviral Responses

We describe a novel function for the interferon (IFN)-induced protein 44-like (IFI44L) gene in negatively modulating innate immune responses induced after virus infections. Furthermore, we show that decreasing IFI44L expression impairs virus production and that IFI44L expression negatively modulates...

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Vydáno v:J Virol
Hlavní autoři: DeDiego, Marta L., Martinez-Sobrido, Luis, Topham, David J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803278/
https://ncbi.nlm.nih.gov/pubmed/31434731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01159-19
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