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Amino Acid Residues Involved in Inhibition of Host Gene Expression by Influenza A/Brevig Mission/1/1918 PA-X

The influenza A virus (IAV) PA-X protein is a virulence factor that selectively degrades host mRNAs leading to protein shutoff. This function modulates host inflammation, antiviral responses, cell apoptosis, and pathogenesis. In this work we describe a novel approach based on the use of bacteria and...

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Détails bibliographiques
Publié dans:Microorganisms
Auteurs principaux: Chiem, Kevin, Martinez-Sobrido, Luis, Nogales, Aitor, DeDiego, Marta L.
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8160905/
https://ncbi.nlm.nih.gov/pubmed/34065592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/microorganisms9051109
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