Vaccination of Macaques with DNA Followed by Adenoviral Vectors Encoding Simian Immunodeficiency Virus (SIV) Gag Alone Delays Infection by Repeated Mucosal Challenge with SIV

Vaccines aimed at inducing T cell responses to protect against human immunodeficiency virus (HIV) infection have been under development for more than 15 years. Replication-defective adenovirus (rAd) vaccine vectors are at the forefront of this work and have been tested extensively in the simian immu...

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Veröffentlicht in:J Virol
Hauptverfasser: Almond, Neil, Berry, Neil, Stebbings, Richard, Preston, Mark, Ham, Claire, Page, Mark, Ferguson, Debbie, Rose, Nicola, Li, Bo, Mee, Edward T., Hassall, Mark, Stahl-Hennig, Christiane, Athanasopoulos, Takis, Papagatsias, Timos, Herath, Shanthi, Benlahrech, Adel, Dickson, George, Meiser, Andrea, Patterson, Steven
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2019
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803269/
https://ncbi.nlm.nih.gov/pubmed/31413132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00606-19
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