Fusion of Ubiquitin to HIV Gag Impairs Human Monocyte-Derived Dendritic Cell Maturation and Reduces Ability to Induce Gag T Cell Responses

The efficient induction of CD8 T cell immunity is dependent on the processing and presentation of antigen on MHC class I molecules by professional antigen presenting cells (APC). To develop an improved T cell vaccine for HIV we investigated whether fusing the ubiquitin gene to the N terminus of the...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Herath, Shanthi, Benlahrech, Adel, Papagatsias, Timos, Athanasopoulos, Takis, Bouzeboudjen, Zineb, Hervouet, Catherine, Klavinskis, Linda, Meiser, Andrea, Kelleher, Peter, Dickson, George, Patterson, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3914991/
https://ncbi.nlm.nih.gov/pubmed/24505475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088327
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados