Langerin negative dendritic cells promote potent CD8(+) T-cell priming by skin delivery of live adenovirus vaccine microneedle arrays

Stabilization of virus protein structure and nucleic acid integrity is challenging yet essential to preserve the transcriptional competence of live recombinant viral vaccine vectors in the absence of a cold chain. When coupled with needle-free skin delivery, such a platform would address an unmet ne...

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Detalhes bibliográficos
Main Authors: Bachy, Veronique, Hervouet, Catherine, Becker, Pablo D., Chorro, Laurent, Carlin, Leo M., Herath, Shanthi, Papagatsias, Timos, Barbaroux, Jean-Baptiste, Oh, Sea-Jin, Benlahrech, Adel, Athanasopoulos, Takis, Dickson, George, Patterson, Steven, Kwon, Sung-Yun, Geissmann, Frederic, Klavinskis, Linda S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581957/
https://ncbi.nlm.nih.gov/pubmed/23386724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1214449110
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