Fragmentation of SIV-gag Vaccine Induces Broader T Cell Responses

BACKGROUND: High mutation rates of human immunodeficiency virus (HIV) allows escape from T cell recognition preventing development of effective T cell vaccines. Vaccines that induce diverse T cell immune responses would help overcome this problem. Using SIV gag as a model vaccine, we investigated tw...

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Detalhes bibliográficos
Main Authors: Benlahrech, Adel, Meiser, Andrea, Herath, Shanthi, Papagatsias, Timos, Athanasopoulos, Takis, Li, Fucheng, Self, Steve, Bachy, Veronique, Hervouet, Catherine, Logan, Karen, Klavinskis, Linda, Dickson, George, Patterson, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485275/
https://ncbi.nlm.nih.gov/pubmed/23118924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048038
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