Fc Gamma Receptor Polymorphisms Modulated the Vaccine Effect on HIV-1 Risk in the HVTN 505 HIV Vaccine Trial

HIV Vaccine Trials Network (HVTN) 505 was a phase 2b efficacy trial of a DNA/recombinant adenovirus 5 (rAd5) HIV vaccine regimen. Although the trial was stopped early for lack of overall efficacy, later correlates of risk and sieve analyses generated the hypothesis that the DNA/rAd5 vaccine regimen...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Li, Shuying S., Gilbert, Peter B., Carpp, Lindsay N., Pyo, Chul-Woo, Janes, Holly, Fong, Youyi, Shen, Xiaoying, Neidich, Scott D., Goodman, Derrick, deCamp, Allan, Cohen, Kristen W., Ferrari, Guido, Hammer, Scott M., Sobieszczyk, Magdalena E., Mulligan, Mark J., Buchbinder, Susan P., Keefer, Michael C., DeJesus, Edwin, Novak, Richard M., Frank, Ian, McElrath, M. Juliana, Tomaras, Georgia D., Geraghty, Daniel E., Peng, Xinxia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803257/
https://ncbi.nlm.nih.gov/pubmed/31434737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02041-18
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