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Murine Leukemia Virus Exploits Innate Sensing by Toll-Like Receptor 7 in B-1 Cells To Establish Infection and Locally Spread in Mice

Lymph-borne Friend murine leukemia virus (FrMLV) exploits the sentinel macrophages in the draining popliteal lymph node (pLN) to infect highly permissive innate-like B-1 cells and establish infection in mice. The reason for FrMLV sensitivity of B-1 cells and their impact on viral spread is unknown....

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Pi, Ruoxi, Iwasaki, Akiko, Sewald, Xaver, Mothes, Walther, Uchil, Pradeep D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803250/
https://ncbi.nlm.nih.gov/pubmed/31434732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00930-19
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