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Murine Leukemia Virus Gag Localizes to the Uropod of Migrating Primary Lymphocytes

B and CD4(+) T lymphocytes are natural targets of murine leukemia virus (MLV). Migrating lymphocytes adopt a polarized morphology with a trailing edge designated the uropod. Here, we demonstrate that MLV Gag localizes to the uropod in polarized B cells and CD4(+) T cells. The uropod localization of...

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Detalhes bibliográficos
Main Authors: Li, Fei, Sewald, Xaver, Jin, Jing, Sherer, Nathan M., Mothes, Walther
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178845/
https://ncbi.nlm.nih.gov/pubmed/24965475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01104-14
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