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Subcellular Localization of HIV-1 gag-pol mRNAs Regulates Sites of Virion Assembly

Full-length unspliced human immunodeficiency virus type 1 (HIV-1) RNAs serve dual roles in the cytoplasm as mRNAs encoding the Gag and Gag-Pol capsid proteins as well as genomic RNAs (gRNAs) packaged by Gag into virions undergoing assembly at the plasma membrane (PM). Because Gag is sufficient to dr...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Becker, Jordan T., Sherer, Nathan M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331792/
https://ncbi.nlm.nih.gov/pubmed/28053097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02315-16
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