The SGLT2 inhibitor dapagliflozin attenuates the activity of ROS-NLRP3 inflammasome axis in steatohepatitis with diabetes mellitus

BACKGROUND: Diabetes mellitus (DM) is considered as a risk factor for the progress of liver diseases. After tissue damage, there is the highest amplitude of ubiquitously sterile inflammatory response in the liver, resulting in a major clinical consequence concerning a high prevalence of steatohepati...

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Publicat a:Ann Transl Med
Autors principals: Leng, Weiling, Wu, Mingxia, Pan, Hang, Lei, Xiaotian, Chen, Liu, Wu, Qinan, Ouyang, Xinshou, Liang, Ziwen
Format: Artigo
Idioma:Inglês
Publicat: AME Publishing Company 2019
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803170/
https://ncbi.nlm.nih.gov/pubmed/31700865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2019.09.03
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