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Molecular free energy profiles from force spectroscopy experiments by inversion of observed committors

In single-molecule force spectroscopy experiments, a biomolecule is attached to a force probe via polymer linkers and the total extension of the molecule plus apparatus is monitored as a function of time. In a typical unfolding experiment at constant force, the total extension jumps between two valu...

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Podrobná bibliografie
Vydáno v:J Chem Phys
Hlavní autoři: Covino, Roberto, Woodside, Michael T., Hummer, Gerhard, Szabo, Attila, Cossio, Pilar
Médium: Artigo
Jazyk:Inglês
Vydáno: AIP Publishing LLC 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803169/
https://ncbi.nlm.nih.gov/pubmed/31640370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.5118362
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