Biological implications of clonal hematopoiesis

Adult hematological malignancies, such as acute myeloid leukemia, are thought to arise through the gradual acquisition of oncogenic mutations within long-lived hematopoietic stem cells (HSCs). Genomic analysis of peripheral blood DNA has recently identified leukemia-associated genetic mutations with...

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Bibliografiske detaljer
Udgivet i:	Exp Hematol
Main Authors:	Luis, Tiago C., Wilkinson, Adam C., Beerman, Isabel, Jaiswal, Siddhartha, Shlush, Liran I.
Format:	Artigo
Sprog:	Inglês
Udgivet:	2019
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6803101/ https://ncbi.nlm.nih.gov/pubmed/31472170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2019.08.004
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Biological implications of clonal hematopoiesis

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