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The ubiquitin ligase adaptor SPOP in cancer
The dysregulation of ubiquitin-mediated proteasomal degradation has emerged as an important mechanism of pathogenesis in several cancers. The Speckle-type POZ Protein (SPOP) functions as a substrate adaptor for the cullin3-RING ubiquitin ligase and controls the cellular persistence of a diverse arra...
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| Pubblicato in: | FEBS J |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6803047/ https://ncbi.nlm.nih.gov/pubmed/31495053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.15056 |
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