IRF1 is critical for the TNF-driven interferon response in rheumatoid fibroblast-like synoviocytes: JAKinibs suppress the interferon response in RA-FLSs

Rheumatoid arthritis (RA) is an autoimmune disease characterized by persistent synovial inflammation. The major drivers of synovial inflammation are cytokines and chemokines. Among these molecules, TNF activates fibroblast-like synoviocytes (FLSs), which leads to the production of inflammatory media...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Exp Mol Med
Main Authors: Bonelli, Michael, Dalwigk, Karolina, Platzer, Alexander, Olmos Calvo, Isabel, Hayer, Silvia, Niederreiter, Birgit, Holinka, Johannes, Sevelda, Florian, Pap, Thomas, Steiner, Günter, Superti-Furga, Giulio, Smolen, Josef S., Kiener, Hans P., Karonitsch, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6802656/
https://ncbi.nlm.nih.gov/pubmed/31285419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-019-0267-6
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker