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mTORC2 activation protects retinal ganglion cells via Akt signaling after autophagy induction in traumatic optic nerve injury

Traumatic optic neuropathy is an injury to the optic nerve that leads to vision loss. Autophagy is vital for cell survival and cell death in central nervous system injury, but the role of autophagy in traumatic optic nerve injury remains uncertain. Optic nerve crush is a robust model of traumatic op...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Wen, Yao-Tseng, Zhang, Jia-Rong, Kapupara, Kishan, Tsai, Rong-Kung
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6802655/
https://ncbi.nlm.nih.gov/pubmed/31409770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-019-0298-z
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