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mTORC2 activation protects retinal ganglion cells via Akt signaling after autophagy induction in traumatic optic nerve injury

Traumatic optic neuropathy is an injury to the optic nerve that leads to vision loss. Autophagy is vital for cell survival and cell death in central nervous system injury, but the role of autophagy in traumatic optic nerve injury remains uncertain. Optic nerve crush is a robust model of traumatic op...

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Bibliografische gegevens
Gepubliceerd in:Exp Mol Med
Hoofdauteurs: Wen, Yao-Tseng, Zhang, Jia-Rong, Kapupara, Kishan, Tsai, Rong-Kung
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6802655/
https://ncbi.nlm.nih.gov/pubmed/31409770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-019-0298-z
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