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Alloactivation of Naïve CD4(+)CD8(−)CD25(+)T Regulatory Cells: Expression of CD8α Identifies Potent Suppressor Cells That Can Promote Transplant Tolerance Induction
Therapy with alloantigen-specific CD4(+)CD25(+) T regulatory cells (Treg) for induction of transplant tolerance is desirable, as naïve thymic Treg (tTreg) are not alloantigen-specific and are weak suppressor cells. Naïve tTreg from DA rats cultured with fully allogeneic PVG stimulator cells in the p...
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| 出版年: | Front Immunol |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2019
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6802415/ https://ncbi.nlm.nih.gov/pubmed/31681288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02397 |
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