Interleukin-5 Mediates Parasite-Induced Protection against Experimental Autoimmune Encephalomyelitis: Association with Induction of Antigen-Specific CD4(+)CD25(+) T Regulatory Cells

OBJECTIVE: To examine if the protective effect of parasite infection on experimental autoimmune encephalomyelitis (EAE) was due to interleukin (IL)-5, a cytokine produced by a type-2 response that induces eosinophilia. We hypothesize that, in parasite infections, IL-5 also promotes expansion of anti...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Tran, Giang T., Wilcox, Paul L., Dent, Lindsay A., Robinson, Catherine M., Carter, Nicole, Verma, Nirupama D., Hall, Bruce M., Hodgkinson, Suzanne J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5671975/
https://ncbi.nlm.nih.gov/pubmed/29163523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01453
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