Human blastocyst outgrowths recapitulate primordial germ cell specification events

Our current knowledge of the mechanisms leading to human primordial germ cell (PGC) specification stems solely from differentiation experiments starting from human pluripotent stem cells. However, information regarding the origin of PGCs in vivo remains obscure. Here we apply an improved system for...

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Foilsithe in:Mol Hum Reprod
Main Authors: Popovic, Mina, Bialecka, Monika, Gomes Fernandes, Maria, Taelman, Jasin, Van Der Jeught, Margot, De Sutter, Petra, Heindryckx, Björn, Chuva De Sousa Lopes, Susana M
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2019
Ábhair:
Original Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6802404/
https://ncbi.nlm.nih.gov/pubmed/31211841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molehr/gaz035
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