Intergenerational effects of sevoflurane in young adult rats

BACKGROUND: Sevoflurane administered to neonatal rats induces neurobehavioral abnormalities and epigenetic reprogramming of their germ cells; the latter can pass adverse effects of sevoflurane to future offspring. As germ cells are susceptible to reprogramming by environmental factors across the lif...

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Gepubliceerd in:Anesthesiology
Hoofdauteurs: Ju, Ling-Sha, Yang, Jiao-Jiao, Xu, Ning, Li, Jia, Morey, Timothy E., Gravenstein, Nikolaus, Seubert, Christoph N., Setlow, Barry, Martynyuk, Anatoly E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6801066/
https://ncbi.nlm.nih.gov/pubmed/31517640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000002920
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