Small molecule grp94 inhibitors with antiviral activity against Dengue and Zika virus

Two major flaviviruses, dengue virus (DENV) and Zika virus (ZIKV), cause severe health and economic burdens worldwide. Recently, genome-wide screenings have uncovered the importance of the Hrd1 ubiquitin ligase-mediated endoplasmic reticulum (ER)-associated degradation (ERAD) pathway for flavivirus...

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Bibliografiske detaljer
Udgivet i:Antiviral Res
Main Authors: Rothan, Hussin A., Zhong, Yongwang, Sanborn, Mark A., Teoh, Teow Chong, Ruan, Jingjing, Yusof, Rohana, Hang, Jun, Henderson, Mark J., Fang, Shengyun
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6801034/
https://ncbi.nlm.nih.gov/pubmed/31421166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2019.104590
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