Small molecule grp94 inhibitors with antiviral activity against Dengue and Zika virus

Two major flaviviruses, dengue virus (DENV) and Zika virus (ZIKV), cause severe health and economic burdens worldwide. Recently, genome-wide screenings have uncovered the importance of the Hrd1 ubiquitin ligase-mediated endoplasmic reticulum (ER)-associated degradation (ERAD) pathway for flavivirus...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Antiviral Res
Egile Nagusiak: Rothan, Hussin A., Zhong, Yongwang, Sanborn, Mark A., Teoh, Teow Chong, Ruan, Jingjing, Yusof, Rohana, Hang, Jun, Henderson, Mark J., Fang, Shengyun
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6801034/
https://ncbi.nlm.nih.gov/pubmed/31421166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2019.104590
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