The epigenetic regulator SIRT6 protects the liver from alcohol-induced tissue injury by reducing oxidative stress in mice

BACKGROUND & AIMS: As an NAD(+)-dependent deacetylase and a key epigenetic regulator, sirtuin 6 (SIRT6) has been implicated in the regulation of metabolism, DNA repair, and inflammation. However, the role of SIRT6 in alcoholic liver disease (ALD) remains unclear. The aim of this study was to inv...

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Publicat a:J Hepatol
Autors principals: Kim, Hyeong Geug, Huang, Menghao, Xin, Yue, Zhang, Yang, Zhang, Xinge, Wang, Gaihong, Liu, Sheng, Wan, Jun, Ahmadi, Ali Reza, Sun, Zhaoli, Liangpunsakul, Suthat, Xiong, Xiwen, Dong, Xiaocheng Charlie
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6801027/
https://ncbi.nlm.nih.gov/pubmed/31295533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2019.06.019
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