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Acid Fasting: Modulation of Mycobacterium tuberculosis metabolism at acidic pH

Mycobacterium tuberculosis (Mtb) senses and adapts to acidic host environments during the course of pathogenesis. Mutants defective in acidic pH-dependent adaptations are often attenuated during macrophage or animal infections, supporting that these pathways are essential for pathogenesis and repres...

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Veröffentlicht in:Trends Microbiol
Hauptverfasser: Baker, Jacob J., Dechow, Shelby J., Abramovitch, Robert B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800632/
https://ncbi.nlm.nih.gov/pubmed/31324436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tim.2019.06.005
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