Efficient electroporation of neuronal cells using synthetic oligonucleotides: identifying duplex RNA and antisense oligonucleotide activators of human frataxin expression

Oligonucleotide drugs are experiencing greater success in the clinic, encouraging the initiation of new projects. Resources are insufficient to develop every potentially important project, and persuasive experimental data using cell lines close to disease target tissue is needed to prioritize candid...

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Veröffentlicht in:RNA
Hauptverfasser: Shen, Xiulong, Beasley, Sharon, Putman, Jennifer N., Li, Yanjie, Prakash, Thahza P., Rigo, Frank, Napierala, Marek, Corey, David R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800520/
https://ncbi.nlm.nih.gov/pubmed/31151992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.071290.119
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