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Sequence-specific m(6)A demethylation in RNA by FTO fused to RCas9
N(6)-methyladenosine (m(6)A) is the most common internal modification in eukaryotic mRNA and associated with numerous cellular processes in health and disease. Up- and down-regulation of its “writer” or “eraser” proteins alter the global m(6)A level; however, modifying distinct m(6)A sites has remai...
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| Pubblicato in: | RNA |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6800472/ https://ncbi.nlm.nih.gov/pubmed/31263003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.070706.119 |
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