Sialic acid mediated mechanical activation of β(2) adrenergic receptors by bacterial pili

Meningococcus utilizes β-arrestin selective activation of endothelial cell β(2) adrenergic receptor (β(2)AR) to cause meningitis in humans. Molecular mechanisms of receptor activation by the pathogen and of its species selectivity remained elusive. We report that β(2)AR activation requires two aspar...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Nat Commun
Hlavní autoři: Virion, Zoe, Doly, Stéphane, Saha, Kusumika, Lambert, Mireille, Guillonneau, François, Bied, Camille, Duke, Rebecca M., Rudd, Pauline M., Robbe-Masselot, Catherine, Nassif, Xavier, Coureuil, Mathieu, Marullo, Stefano
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800425/
https://ncbi.nlm.nih.gov/pubmed/31628314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12685-6
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky