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Mapping low-affinity/high-specificity peptide–protein interactions using ligand-footprinting mass spectrometry
Short linear peptide motifs that are intracellular ligands of folded proteins are a modular, incompletely understood molecular interaction language in signaling systems. Such motifs, which frequently occur in intrinsically disordered protein regions, often bind partner proteins with modest affinity...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6800362/ https://ncbi.nlm.nih.gov/pubmed/31578253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1819533116 |
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