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Computational and informatics strategies for identification of specific protein interaction partners in affinity purification mass spectrometry experiments

Analysis of protein interaction networks and protein complexes using affinity purification and mass spectrometry (AP/MS) is among most commonly used and successful applications of proteomics technologies. One of the foremost challenges of AP/MS data is a large number of false positive protein intera...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: Nesvizhskii, Alexey I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744239/
https://ncbi.nlm.nih.gov/pubmed/22611043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201100537
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