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Computational and informatics strategies for identification of specific protein interaction partners in affinity purification mass spectrometry experiments

Analysis of protein interaction networks and protein complexes using affinity purification and mass spectrometry (AP/MS) is among most commonly used and successful applications of proteomics technologies. One of the foremost challenges of AP/MS data is a large number of false positive protein intera...

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Bibliografische gegevens
Hoofdauteur: Nesvizhskii, Alexey I.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744239/
https://ncbi.nlm.nih.gov/pubmed/22611043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201100537
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