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SAINT-MS1: protein-protein interaction scoring using label-free intensity data in affinity purification – mass spectrometry experiments

We present a statistical method SAINT-MS1 for scoring protein-protein interactions based on the label-free MS1 intensity data from affinity purification - mass spectrometry (AP-MS) experiments. The method is an extension of Significance Analysis of INTeractome (SAINT), a model-based method previousl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Choi, Hyungwon, Glatter, Timo, Gstaiger, Mathias, Nesvizhskii, Alexey I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744231/
https://ncbi.nlm.nih.gov/pubmed/22352807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr201185r
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